EVALUATION OF OIL BASED AVIAN INFLUENZA VACCINE (H5NI) PREPARED WITH DIFFERENT
CONCENTRATIONS OF ADJUVANT
M. IQBAL, MARYAM NISAR, ANWARUL-HAQ, SHOAIB NOOR AND Z.J.GILL
Veterinary Research Institute,
flu vaccine from H5N1 strain of avian influenza virus was prepared with two
concentrations of adjuvant (Montanide ISA 70MVG). Two vaccines (I and II) were
prepared containing 50 and 60% Montanide, respectively. Immune response of both
the vaccines as single, as well as booster, dose was evaluated in layer birds
through haemagglutination inhibition test. Single dose of both vaccines showed
poor immune response, while booster dose gave better response with both the
vaccines. However, the vaccine prepared with 60% Montanide provided better
immune response compared with the vaccine containing 50% montanide.
Birdflu vaccine, HI titre, H5N1 avian influenza virus,oil based vaccine.