Most neoplasms located in the posterior part of the eyeball pose a serious diagnostic challenge. An early diagnose and appropriate treatment of such neoplasms is crucial for the successful outcome, reflected in the survival of the affected animal. The present clinical case describes an 11-year-old male Poodle dog presented with blepharospasm, epiphora and progressive ocular irritation in the right eye, accompanied by pain, inflammation and proptosis of the ocular globe. The dog had a history of having received treatment for conjunctivitis with ophthalmic antibiotics without any improvement. Ophthalmologic examination of the dog revealed unilateral proptosis of the ocular globe with ventrolateral deviation, conjunctivitis, erythema, partial vision loss, elevated intraocular pressure and pain upon palpation. Computed Tomography imaging revealed a 5.11cm² solid retrobulbar mass affecting the optic nerve without compromising the orbital socket. Histopathological and the immunohistochemistry test for vimentin examination confirmed the presence of Grade II retrobulbar sarcoma. The Ki-67 marker was below 30%, which indicated a favorable prognosis for the survival of the dog. Exenteration proved to be the appropriate treatment, with a successful post-operative outcome and no recurrence was observed during seven months of follow-up, ensuring a prolonged quality of life for the affected dog.

To Cite This Article: Goicochea-Vargas JF, Rondón-Jorge W, Acosta-Pachorro F, Montalvo-Cotrina L, Pio-Rivera k, Ratto -Valderrama V, Morales-Parra E and Salvatierra-Alor M, 2025. Retrobulbar Sarcoma in a Poodle Dog: Diagnosis and Surgical Management. Pak Vet J, 45(1): 454-457. http://dx.doi.org/10.29261/pakvetj/2025.141