The experiment was carried out on 600 day old broiler chicks randomly divided into four groups designated as T₀, T₁, T₂ and T₃ with 150 birds in each group for a period of 42 days to find out the effect of different oil supplements on humoral immune response and lipid profile. All groups were maintained on isonitrogenous feed supplemented with soyabean oil (T₁); palm oil (T₂) and fish oil (T₃) @ 2.5%. The birds of group T₀ were maintained as untreated controls without addition of any oil supplement. All birds were vaccinated against Newcastle disease virus (NDV) on 0 and 7^th day. Weekly collected serum samples were analyzed for determination of antibody titer against NDV and lipid profile through haemagglutination inhibition (HI) and calorimetric method respectively. Fatty acid profile in abdominal fat was determined through gas chromatographic analysis. On 28^th day of age, highest geometric mean antibody titer against NDV was recorded for T₂ (776) group followed by T₁ (256); T₃ (157) and T₀ (39.4). On 42^nd day, significantly (P<0.05) decreased HDL (18.33±0.67 mg/dl) and triglycerides (93±5.49 mg/dl) were recorded for group T₁ whereas that of LDL (67.67±1.71 mg/dl) was recorded for group T₃. Non-significant (P>0.05) difference was recorded between the groups with respect to unsaturated and saturated fatty acids in abdominal fat. It was concluded that palm oil supplement significantly increased the humoral immune response as compared to soybean and fish oil supplements.

Key words: Broiler, Humoral immune response, Lipid profile, NDV, Oil supplement