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Influence of Dietary Supplementation with Selenium on Blood Metabolic Profile and Thyroid Hormones Activities in Fattening Lambs
 
Z Antunović1*, J Novoselec1, M Šperanda1, T Klapec2, S Ćavar3, B Mioč4, Ž Klir1, V Pavić5 and R Vuković5
 
1Faculty of Agriculture, University of Josip Juraj Strossmayer in Osijek, K. Petra Svacica 1 d, 31000 Osijek, Croatia; 2Faculty of Food Technology, University of Josip Juraj Strossmayer in Osijek, Kuhaceva 18, 31000 Osijek, Croatia; 3Institute of Public Health for Osijek-Baranya County, F. Krezme 1, 31000 Osijek, Croatia; 4Faculty of Agriculture, University of Zagreb, Svetosimunska cesta 25, 10000 Zagreb, Croatia; 5Department of Biology, University of Josip Juraj Strossmayer in Osijek, C. Hadrijana 8/A, 31000 Osijek, Croatia
*Corresponding author: zantunovic@pfos.hr

Abstract   

The aim of the investigation was to determine influence of dietary supplementation with selenium on blood metabolic profile and thyroid hormones activities in fattening lambs. The study included 36 Merinolandschaf lambs during fattening period (50 days) divided into three groups (control, Exp-I and Exp-II). The control group diet was not supplemented with Se, whereas the diet of Exp-I was supplemented with 0.3 mg/kg inorganic selenium (sodium selenite) and Exp-II with 0.3 mg/kg organic selenium (Sel-Plex). Concentration of minerals (Ca, P-inorganic, K, Na, Fe and Cl), biochemical indicators (urea, glucose, cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, creatinine, total protein, albumin), enzyme activity (ALT, AST, GGT, LDH and GSH-Px) and thyroid hormone activities (T3, T4) were determined. Significantly higher (P<0.01) selenium content and GSH-Px activity as well as the lower content of Ca was determined in the blood of Exp-II and Exp-I groups compared to control group (93.89 and 67.69: 34.11 µg L-1; 607.98 and 556.92: 247.52 µkat L-1; 2.38 and 2.39: 2.76 mmol L-1). Significantly higher (P<0.01) selenium content in the in blood of lambs from Exp-II compared to Exp-I group was determined. Significantly higher (P<0.05) concentrations of HDL-cholesterol and T3 hormone activity were found in Exp-II group compared to the Exp-I and control groups. The results showed lower blood selenium content in control group and indicate the justification of adding selenium, especially organic selenium in lamb’s diets, raising the concentration of Se, GSH-Px enzyme, HDL-cholesterol and T3 hormones improving the health status, especially in areas deficient in selenium.

Key words: Biochemical parameters, Blood, Lambs, Selenium, Thyroid hormones

 
   

ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)



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